Latest Research Conclusion 2015 :-

        Research By VR Foundation In 2015 :- 

   
     I Hope you enjoyed your summer. It's been a busy one for us at VRF, So there's lots to report In this month's newsletter. First, Let's talk about some news on early treatment diagnosis, which is of critical importance as early treatment produces better and long lasting results. Recent research has shown that a hand-held 'black light'. which is commonly used to locate stains around the house or find counterfeit currency , can also detect early-stage vitiligo. This is instead of a specialized wood's lamp, which is bulky and expensive. 

     Talking of research, Recently, we did some of our research into "traditional medicines' and other possible ethono-pharmacological shortcuts in the research for effective treatments. Indigenous cultures possess notions, to a remarkable extents, of how different plants can be used to treat skin diseases. Of course, plant treatments need to be approached with caution, given issues of possible toxicity, so we have published an FAQ section on this subject on our website.

     Now for some support news.Larry (A.K.A Spotty) King Has recently launched vitiligomatch to help the community. This social site is a place where people with vitiligo and their friends and supporters can chat, exchange photos and generally 'fell at home'. Make sure you take a look. 

 Thank You.

MELBILD

Melbild          

 For The Use Of A Registered Medical Practitioner Or Hospital Or Vitiliogo Patient. 

 

Melbild is a tropical preparation for management  of vitiligo. It is Available in two Strengths and use for external use only.

 1.  What is Melbild ?

 =  It is a sequence of amino acids derived from basic fibroblast growth factor (bFGF). It Stimulates growth  of melanocytes and therefore helps in repigmenting the depigmented skin.

With the use of such preparations one can expect some noticeable change in about 3-6 months.

Significant repigmentation may be achieved with continued use for about a year.

 2. How Is MELBILD To Be Used ?

 = To Begin with , Remove the plug of the MELBILD container and replace it with a roller. Gently, Shake the bottle , and then apply. Before applying MELBILD, Clean and dry the affected area thoroughly, and then apply as a very thin film.

It is best to apply MELBILD some 2 hours before retiring for the night. Every morning, the treated patches may be exposed to sunlight for 10-15 minutes. If this not possible, the treated patches may be exposed to commercially available Ultraviolet Lamps.

3. How Is MELBILD To Be Stored ?

= MELBILD is to be stored at a temperature below 25 degree Celsius and away from light, to maintain optimal effectiveness.

Thank You. Please comment  below for all information of vitiligo .

New Medicine for vitiligo (CXCL 10) . The Light of hope.

New Medicine for vitiligo. MUST READ :

In the lab , Experts focus on two aspects of Vitiligo :-

Firstly , They study how abnormal , "stressed" melanocytes alert the immune system to their presence. Once stressed , melanocytes produce signals , that recruit T cells to the skin , which then find the melanocytes and kill them.

Secondly , They study how the T cells detect these signals , enter the skin , find the melanocytes , and kill them.

For the seek of vitiligo patients , experts use mouse as model , that had white spot on there body as shown in figure :-

Examining these mice from many angles , their disease looks very similar to human vitiligo . The benefit of this system is the powerful tools available to study diseases in mice. They are developing humanized mouse model of vitiligo ,  where they transfer human T cells , or both T cells and skin , from vitiligo patients to immunosuppressed mice that permit the growth of human tissues. The benefit of this system is the ability to study human T cells and skin and it has the potential to test new treatment on human tissues before attempting clinical trials.

 They are conducting a clinical trial to investigate new drug as treatment for vitiligo :- 

They were able to identify one of the critical pathways used by T cells to crawl into the skin and find melanocytes. The first signal in the pathway is IFN-g , a protein made by immune cells , which act as a powerful master switch to turn on immune responses. IFN-g then turns on CXCL10, which is required for the ability of T-cells to find melanocytes and kill them. Imagine , an ant that has found a new piece of food on the ground. The ant then lays a chemical trail that others follow to the food.CXCL10 acts acts like that chemical trail , promoting both proper   localization of T cells to Find the melaocytes , and also increase their determination to kill them. There are existing drugs that have been developed by pharmaceutical companies that block the ability of CXCL10 to function in humans, and so they may be effective treatments in vitiligo as well.

They have also begun to identify the signals produced by stressed melaocytes that activate immune cells. We believe that studying the communication between stressed melanocytes and immune cells will tells us how vitiligo gets started in the first place, and how to better prevent its onset and spread.

Recently done clinical trial upon mice , stunts all , as shown in figure :-

Stay with us for latest news on this topics as i consult with some expert and take there reviews .